Alzheimer's disease (AD), also referred to simply as Alzheimer's, is a chronic neurodegenerative disease that usually starts slowly and worsens over time. It is the cause of 60% to 70% of cases of dementia. The most common early symptom is difficulty in remembering recent events (short-term memory loss). As the disease advances, symptoms can include problems with language, disorientation (including easily getting lost), mood swings, loss of motivation, not managing self care, and behavioural issues. As a person's condition declines, they often withdraw from family and society. Gradually, bodily functions are lost, ultimately leading to death. Although the speed of progression can vary, the average life expectancy following diagnosis is three to nine years.

World Alzheimer's Day - 2020

World Alzheimer's Day was launched at the opening of ADI's annual conference in Edinburgh on 21 September 1994 to celebrate our 10th anniversary. World Alzheimer's Day is on 21 September each year. While World Alzheimer's Month offers a longer period of time for Alzheimer associations worldwide to raise awareness, World Alzheimer's Day marks the pinnacle of the Month.

World Alzheimer's Day - 2019

World Alzheimer's Day was launched at the opening of ADI's annual conference in Edinburgh on 21 September 1994 to celebrate our 10th anniversary. World Alzheimer's Day is on 21 September each year. While World Alzheimer's Month offers a longer period of time for Alzheimer associations worldwide to raise awareness, World Alzheimer's Day marks the pinnacle of the Month.

Improving the Quality of Life for Dementia Patients through Progressive Detection, Treatment, and Care

The prominence of dementia within the global aging population has undergone an increase in recent years. To improve the living conditions of patients, researchers must place more emphasis on early detection methods. Improving the Quality of Life for Dementia Patients through Progressive Detection, Treatment, and Care provides a thorough overview of emerging research on various neuroscience methods for the early diagnosis of dementia and focuses on the improvement of healthcare delivery to patients.

PPARγ-coactivator-1α gene transfer reduces neuronal loss and amyloid-β generation by reducing β-secretase in an Alzheimer’s disease model

Current therapies for Alzheimer’s disease (AD) are symptomatic and do not target the underlying Aβ pathology and other important hallmarks including neuronal loss. PPARγ-coactivator-1α (PGC-1α) is a cofactor for transcription factors including the peroxisome proliferator-activated receptor-γ (PPARγ), and it is involved in the regulation of metabolic genes, oxidative phosphorylation, and mitochondrial biogenesis.

Alzheimer's Disease International

Alzheimer's Disease International website image

Alzheimer's Disease International (ADI) believes that the key to winning the fight against dementia lies in a unique combination of Global Solutions and local knowledge. As such, it works locally, by empowering Alzheimer associations to promote and offer care and support for people with dementia and their carers, while working globally to focus attention on dementia. Our board is composed of people from around the world, and our staff team is based in London.

World Alzheimer's Day - 2018

World Alzheimer's Day was launched at the opening of ADI's annual conference in Edinburgh on 21 September 1994 to celebrate our 10th anniversary. World Alzheimer's Day is on 21 September each year. While World Alzheimer's Month offers a longer period of time for Alzheimer associations worldwide to raise awareness, World Alzheimer's Day marks the pinnacle of the Month.

World Alzheimer's Day - 2017

World Alzheimer's Day was launched at the opening of ADI's annual conference in Edinburgh on 21 September 1994 to celebrate our 10th anniversary. World Alzheimer's Day is on 21 September each year. While World Alzheimer's Month offers a longer period of time for Alzheimer associations worldwide to raise awareness, World Alzheimer's Day marks the pinnacle of the Month.